Great premise, great cliffhanger.
I like the artwork of it in general. There's something incredibly macabre about it from the first screen, even before you really know what's happening. And having gone through the first act, I see the narration text has gotten a lot more erratic, and it works to your credit, because it just gives that added touch of foreboding. I might as well mention here: The music is really fitting. The way it flits between ominous background noises and the guitar, and yet still maintains the mood perfectly. Really nice choice, there.
I got a few vague Saw vibes? From the antagonist-in-the-TV, do-something-horrible-or-bad-things-w ill-happen idea, but the parallel pretty much draws to a close straight after that. This has a fresh kind of creepiness to it. I think the fact it's a frame-by-frame comic and not a flash just adds to the melancholy aspect of this; like it would be less scary if it was all totally moving.
The "GOD NO" reply from the guy during the dialogue seemed a little superfluous, and almost distracting from the demands the TV-man was making. But apart from that, the premise is set well and all you needed do at that point is make something utterly disturbing to bring the scene to a peak.
Which you did. Marvellously. I could be a pedant and say "You couldn't cut a nose clean off like that with one swipe of scissors", but I think the bounds of reality can be stretched a little given how utterly disturbing the image is itself.
However, the "AAA" in his reaction-shot was again, a little distracting. I almost wish you'd found a non-textual way to convey his reaction, as it's obvious that he'd be horrified and in absolute pain, and it's obvious that you can create certain emotions in the backdrop and artwork in general, anyway.
The abrupt flick-back to Mr. Jaw in the alleyway was also a nice touch, as you leave the now-noseless man simultaneously at his cliffhanger and conclusion-you almost know that he'll carry out all the other tasks asked of him, and yet you're unsure as to whether he'll be able to do it.
And if that wasn't enough, you've got the closing line implying that Mr. Jaw's vendetta has barely even started. So it's safe to say you've gained a follower here. I have a need to know what happens next. Great work.
-Review Request Club